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How Long Does It Take For HRT To Start Working?

How Long Does It Take For HRT To Start Working?

There isn’t a specific day that hormone therapy starts working. The HRT timeline for each person is different. While some patients see changes shortly after treatment initiation, others can take longer to see the effects.

However, on average, it usually takes 3-4 weeks before you will feel the initial benefits of HRT and up to three months to feel the full effects. 

Women frequently see hot flashes and night sweats improve or disappear within days to weeks. Positive changes in energy levels, vitality, mood, sleep, sex drive, memory and skin quality soon follow. 

Male patients on testosterone therapy usually experience the return of higher energy levels, improved thinking, improved sex drive and performance, and an overall improved sense of well-being within a few weeks. 

Paul E. Cox, M.D., MS
Vital Living Healthcare

Contact 404.843.3636,

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